All functions

DDARawData

Example dataset from a label-free DDA, a controlled spike-in experiment.

DDARawData.Skyline

Example dataset from a label-free DDA, a controlled spike-in experiment, processed by Skyline.

DIARawData

Example dataset from a label-free DIA, a group comparison study of S.Pyogenes.

DIAUmpiretoMSstatsFormat()

Import DIA-Umpire files

MSstatsContrastMatrix()

Create a contrast matrix for groupComparison function

MSstatsGroupComparison()

Group comparison

MSstatsGroupComparisonOutput()

Create output of group comparison based on results for individual proteins

MSstatsGroupComparisonSingleProtein()

Group comparison for a single protein

MSstatsHandleMissing()

Handle censored missing values

MSstatsMergeFractions()

Re-format the data before feature selection

MSstatsNormalize()

Normalize MS data

MSstatsPrepareForDataProcess()

Prepare data for processing by `dataProcess` function

MSstatsPrepareForGroupComparison()

Prepare output for dataProcess for group comparison

MSstatsPrepareForSummarization()

Prepare feature-level data for protein-level summarization

MSstatsSelectFeatures()

Feature selection before feature-level data summarization

MSstatsSummarizationOutput()

Post-processing output from MSstats summarization

MSstatsSummarize()

Feature-level data summarization

MSstatsSummarizeSingleLinear()

Linear model-based summarization for a single protein

MSstatsSummarizeSingleTMP()

Tukey Median Polish summarization for a single protein

MaxQtoMSstatsFormat()

Import MaxQuant files

OpenMStoMSstatsFormat()

Import OpenMS files

OpenSWATHtoMSstatsFormat()

Import OpenSWATH files

PDtoMSstatsFormat()

Import Proteome Discoverer files

ProgenesistoMSstatsFormat()

Import Progenesis files

SRMRawData

Example dataset from a SRM experiment with stable isotope labeled reference of a time course yeast study

SkylinetoMSstatsFormat()

Import Skyline files

SpectronauttoMSstatsFormat()

Import Spectronaut files

checkRepeatedDesign()

Check if data represents repeated measurements design

dataProcess()

Process MS data: clean, normalize and summarize before differential analysis

dataProcessPlots()

Visualization for explanatory data analysis

designSampleSize()

Planning future experimental designs of Selected Reaction Monitoring (SRM), Data-Dependent Acquisition (DDA or shotgun), and Data-Independent Acquisition (DIA or SWATH-MS) experiments in sample size calculation

designSampleSizePlots()

Visualization for sample size calculation

getProcessed()

Get feature-level data to be used in the MSstatsSummarizationOutput function

getSamplesInfo()

Get information about number of measurements for each group

getSelectedProteins()

Get proteins based on names or integer IDs

groupComparison()

Whole plot testing

groupComparisonPlots()

Visualization for model-based analysis and summarizing differentially abundant proteins

makePeptidesDictionary()

Prepare a peptides dictionary for global standards normalization

modelBasedQCPlots()

Visualization for model-based quality control in fitting model

quantification()

Protein sample quantification or group quantification

savePlot()

Save a plot to pdf file

theme_msstats()

Theme for MSstats plots